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KMID : 1149520180020020097
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Cardiovasclar Imaging Asia
2018 Volume.2 No. 2 p.97 ~ p.106
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Role of Noninvasive Diagnostic Imaging in Cardiac Amyloidosis: A Review
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Oda Seitaro
Utsunomiya Daisuke
Nakaura Takeshi
Takashio Seiji
Izumiya Yasuhiro
Tsujita Kenichi
Ueda Mitsuharu
Yamashita Taro
Ando Yukio
Kawano Yawara
Okuno Yutaka
Hata Hiroyuki
Yamashita Yasuyuki
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Abstract
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Historically, cardiac amyloidosis (CA) has been considered a rare disease; however, recent research has revealed a considerable number of hidden CA cases in patients with heart failure, especially in those with heart failure with preserved ejection fraction, implying that the actual incidence of CA is probably underestimated. Typically, cardiac involvement signifies a poor prognosis in patients with systemic amyloidosis. However, recent advancements in therapeutic interventions have contributed to improved prognosis in these patients. Apparently, early diagnosis and intervention with effective therapies are imperative, because adequate therapeutic effects are not achieved in patients with late-stage CA. Advanced diagnostic imaging modalities, such as echocardiography, cardiac magnetic resonance imaging, and bone scintigraphy, facilitate a precise and early diagnosis of CA, providing appropriate management to patients with CA. This review aims to outline the clinical features of CA and the recent advancements in noninvasive diagnostic approaches using imaging modalities for CA.
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KEYWORD
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Amyloidosis, Heart failure, Cardiomyopathies, Cardiac imaging techniques, Magnetic resonance imaging
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